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The value of the Zio service has been demonstrated in over 100 original scientific research manuscripts.1

Publications

Moss et al, Heart Rhythm, 2023

Simultaneous comparison of patch versus multi-electrode cardiac monitoring for the detection of arrhythmias: The COMPARE study.
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Savur et al, IEEE J Biomed Heal Inform, 2023

Monitoring Pulse Rate in the Background Using Front Facing Cameras of Mobile Devices.
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Gadaleta et al, NPJ Digit Med. 2023

Prediction of atrial fibrillation from at-home single-lead ECG signals without arrhythmias.
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Raghunath et al, J Electrocardiol., 2023

An ECG-based machine learning model for predicting new-onset atrial fibrillation is superior to age and clinical features in identifying patients at high stroke risk.
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Chaitoff et al, J Gen Intern Med., 2023

Patient-Centered Outcomes in Clinical Trials of Wearable Devices for Atrial Fibrillation.
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Irie et al, Int Hear J., 2023

The Relationship between Holter Electrocardiography and Atrial Fibrillation Diagnosis Using Real-World Data in Japan: A Claims-Based Retrospective Study.
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Hong et al, Cambridge University Press, 2023

Cardiac arrhythmias in postural tachycardia syndrome and orthostatic intolerance.
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Etzkorn et al, Stat Biosci., 2023

Classification of Free-Living Body Posture with ECG Patch Accelerometers: Application to the Multicenter AIDS Cohort Study.
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Mustapha et al, JACC: Advances, 2023

Association Between Left Ventricular Scar and Ventricular Ectopy in People Living With and Without HIV.
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Yang et al, JACC: Heart Failure, 2023

Prevalence of Subclinical Atrial Fibrillation in Heart Failure With Preserved Ejection Fraction.
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Yoshida et al, J Am Heart Assoc, 2023

Subclinical Left Ventricular Dysfunction and Ventricular Arrhythmias in Older Adults With Normal Ejection Fraction.
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Poh et al, JAHA, 2023

Validation of a Deep Learning Algorithm for Continuous, Real‐Time Detection of Atrial Fibrillation Using a Wrist‐Worn Device in an Ambulatory Environment.
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Goergen et al, Heart Rhythm, 2023

A Comparison of Data Quality and Monitoring Completion Rates Between Clinic and Self-Applied ECG Patches.
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Marcus et al, New Engl J Med, 2023

Acute Effects of Coffee Consumption on Health among Ambulatory Adults.
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Reynolds et al, American Heart Journal, 2023

Comparative Effectiveness and Healthcare Utilization for Ambulatory Cardiac Monitoring Strategies in Medicare Beneficiaries.
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Austin et al, J Am Heart Assoc, 2022

Left Atrial Function and Arrhythmias in Relation to Small Vessel Disease on Brain MRI: The Multi-Ethnic Study of Atherosclerosis.
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Gubitosi-Klug et al, Diabetes Care, 2022

Continuous Glucose Monitoring in Adults With Type 1 Diabetes With 35 Years Duration From the DCCT/EDIC Study.
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Chen et al, JAMA Health Forum., 2022

Cost-effectiveness of Screening for Atrial Fibrillation Using Wearable Devices.
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Gillett et al, Cannabis Cannabinoid Res., 2022

Arrhythmic Effects of Cannabis in Ischemic Heart Disease.
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Reynbakh et al, Am Heart J Plus, 2022

Arrhythmia patterns during and after hospitalization for COVID-19 infection detected via patch-based mobile cardiac telemetry.
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Pothineni et al, J Stroke Cerebrovasc Dis, 2022

Continuous cardiac rhythm monitoring post-stroke: A feasibility study in REGARDS.
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Harding et al, American Journal of Cardiology, 2022

Self-reported marijuana use and cardiac arrhythmias (from the Multiethnic Study of Atherosclerosis).
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Etzkorn et al, AIDS, 2022

Patterns of objectively measured physical activity differ between men living with and without HIV.
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Huber et al, J Am Heart Assoc, 2022

Left Atrial Strain and the Risk of Atrial Arrhythmias From Extended Ambulatory Cardiac Monitoring: MESA.
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Tarakji et al, Heart Rhythm, 2022

Bradyarrhythmias detected by extended rhythm recording in patients undergoing transcatheter aortic valve replacement (Brady-TAVR Study).
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Pang et al, Epilepsy Behav., 2022

Epileptic seizures and Epilepsy Monitoring Unit admission disclose latent cardiac electrical instability.
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Okoh et al, Catheterization & Cardiovascular Interventions, 2022

Utilizing ambulatory electrocardiogram monitoring to reduce conduction related death after transcatheter aortic valve replacement.
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Dewland et al, Open Heart, 2022

Prospective arrhythmia surveillance after a COVID-19 diagnosis.
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Lang et al, Future Health J., 2022

Process and Systems: Improving stroke pathways using an adhesive ambulatory ECG patch: reducing time for patients to ECGs and subsequent results.
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Johansen et al, J Alzheimers Dis, 2022

Associations Between Atrial Arrhythmias and Brain Amyloid Deposition: The ARIC-PET Study.
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McCarthy et al, J Thorac Cardiovasc Surg., 2022

Three-year outcomes of the postapproval study of the AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation Trial.
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Ma et al, American Journal of Cardiology, 2022

Life’s Simple 7 Cardiovascular Health Score in Relation to Arrhythmias on Extended Ambulatory Electrocardiographic Monitoring (from the Multi-Ethnic Study of Atherosclerosis).
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Gupta et al., The American Journal of Cardiology, 2021

Diagnostic Yield, Outcomes, and Resource Utilization With Different Ambulatory Electrocardiographic Monitoring Strategies.
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Kim et al, J Am Soc Nephrol., 2021

Two-Week Burden of Arrhythmias across CKD Severity in a Large Community-Based Cohort: The ARIC Study.
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Norby et al, Neurology., 2021

Association of Ventricular Arrhythmias With Dementia: The Atherosclerosis Risk in Communities (ARIC) Study.
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Muntané-Carol et al, JACC Cardiovasc Interv., 2021

Ambulatory Electrocardiographic Monitoring Following Minimalist Transcatheter Aortic Valve Replacement.
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McIntyre et al, Crit Care Explorations., 2021

High Sensitivity Estimate of the Incidence of New-Onset Atrial Fibrillation in Critically Ill Patients.
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Krishnappa et al, Int J Cardiol., 2021

Life's Simply 7 cardiovascular health score and premature atrial contractions: The atherosclerosis risk in communities (ARIC) study.
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Assis et al, J Cardiovasc Electrophysiol., 2021

Efficacy of catheter ablation for premature ventricular contractions in arrhythmogenic right ventricular cardiomyopathy.
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Garg et al., The American Journal of Cardiology, 2021

Association of Longitudinal Changes in Cardiac Biomarkers With Atrial and Ventricular Arrhythmias (from the Atherosclerosis Risk in Communities [ARIC] Study).
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Mannina et al, International Journal of Cardiology., 2021

Frequency of cardiac arrhythmias in older adults: Findings from the Subclinical Atrial Fibrillation and Risk of Ischemic Stroke (SAFARIS) study.
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Gladstone et al., JAMA Cardiology, 2021

Screening for Atrial Fibrillation in the Older Population – A Randomized Clinical Trial.
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Feinstein et al, AIDS [Internet]., 2021

Ventricular ectopy and arrhythmia by HIV serostatus, viremia, and CD4+ cell count.
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Nawab et al, Clin Kidney J., 2021

Accelerometer-measured physical activity and functional behaviours amoung people on dialysis.
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Wang et al, J Am Heart Assoc., 2021

Differences in Left Atrial Size and Function and Supraventricular Ectopy Between Black and White Participants in the ARIC Study.
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Cho et al, PLoS One., 2021

Delayed repolarization and ventricular tachycardia in patients with heart failure and preserved ejection fraction.
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Marcus et al, Ann Intern Med., 2021

Acute Consumption of Alcohol and Discrete Atrial Fibrillation Events.
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Steinhubl et al, PLoS One., 2021

Three year clinical outcomes in a nationwide, observational, siteless clinical trial of atrial fibrillation screening -mHealth Screening to Prevent Strokes (mSToPS).
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Rooney et al, Mayo Clin Proc., 2021

Frequent Premature Atrial Contractions Are Associated With Poorer Cognitive Function in the Atherosclerosis Risk in Communities (ARIC) Study.
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Osuji et al, Medicine (Baltimore)., 2021

Association between human immunodeficiency virus serostatus and the prevalence of atrial fibrillation.
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Brunetti et al, Pacing Clin Electrophysiol., 2021

New-onset atrial fibrillation in intensive care: epidemiology and outcomes.
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Tarakji et al., Heart Rhythm Journal, 2021

Bradyarrhythmias Detected by Extended Rhythm Recording in Patients Undergoing Transcatheter Aortic Valve Replacement (Brady-TAVR Study).
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D’Souza et al, Am J Epidemiol., 2021

Characteristics of the MACS/WIHS Combined Cohort Study: Opportunities for Research on Aging With HIV in the Longest US Observational Study of HIV.
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Carruth et al, Circ Genom Precis Med., 2021

Clinical Findings and Diagnositc Yield of Arrhythmogenic Cardiomyopathy Through Genomic Screening of Pathogenic or Likely Pathogenic Desmosome Gene Variants.
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Alonso et al, Nutr Metab Cardiovasc Dis, 2020

Circulating electrolytes and the prevalence of atrial fibrillation and supraventricular ectopy: The Atherosclerosis Risk in Communities (ARIC) study.
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DeLurgio et al, Circ Arrhythm Electrophysiol., 2020

Hybrid Convergent Procedure for the Treatment of Persistent and Long-Standing Persistent Atrial Fibrillation: Results of CONVERGE Clinical Trial.
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Full et al, Sleep Breath, 2020

Association between excessive daytime sleepiness and measures of supraventricular arrhythmia burden: evidence from Atherosclerosis Risk in Communities (ARIC) study.
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Harding et al, Pharmacoepidemiol Drug Saf, 2020

Opiod, gabapentinoid, and nonsteroidal anti-inflammatory medication use and the risks of atrial fibrillation and supraventricular ectopy in the Multi-Ethnic Study of Atherosclerosis.
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Braunstein et al, J Cardiovasc Electrophysiol., 2020

Inpatient cardiac monitoring using a patch-based mobile cardiac telemetry system during the COVID-19 pandemic.
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Heo et al., Cardiovasc Diabetol, 2020

Chronic kidney disease and undiagnozed atrial fibrillation in individuals with diabetes.
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Heravi et al., Circulation, 2020

HIV Infection is Associated With Variability in Ventricular Repolarization.
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Wang et al., Am J Cardiol., 2020

Association of Life's Simple 7 with Atrial Fibrillation Burden (From the Atherosclerosis Risk in Communities Study).
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Gunasekaran et al., Pacing Clin Electrophysiol., 2020

Left ventricular extracellular volume expansion does not predict recurrence of atrial fibrillation following catheter ablation.
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Khan et al., Front Neurol., 2020

Fast-Track Long Term Continuous Heart Monitoring in a Stroke Clinic: A Feasibility Study.
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Quer et al., Europace., 2020

Screening for atrial fibrillation: predicted sensitivity of short, intermittent electrocardiogram recordings in an asymptomatic at-risk population.
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Eysenck et al., J Interv Card Electrophysiol., 2020

A randomized trial evaluating the accuracy of AF detection by four external ambulatory ECG monitors compared to permament pacemaker AF detection.
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Waalen et al., Heart Rhythm O2, 2020

Healthcare Resource Utilization Following ECG Sensor Patch Screening for Atrial Fibrillation.
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Rooney et al., J Electrocardiol., 2020

Serum magnesium and burden of atrial and ventricular arrhythmias: The Atherosclerosis Risk in Communities (ARIC) Study.
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Kim et al., J Electrocardiol., 2020

Diurnal circadian variations in paroxysmal atrial fibrillation: The atherosclerosis risk in communities (ARIC) study.
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Heckbert et al, Circ Arrhythmia Electrophysiol., 2020

Differences by Race/Ethnicity in the Prevalence of Clinically Detected and Monitor-Detected Atrial Fibrillation.
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Kaura et al., European Journal of Medical Research, 2019

Early Prolonged Ambulatory Cardiac Monitoring in Stroke (EPACS): An Open-Label Randomised Controlled Trial.
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Yenikomshian et al., Current Medical Research and Opinion, 2019

Cardiac Arrhythmia Detection Outcomes Among Patients Monitored With the Zio Patch System: A Systematic Literature Review.
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Rooney et al., Circ Arrhythmia Electrophysiol., 2019

Prevalence and Characteristics of Subclinical Atrial Fibrillation in a Community-Dwelling Elderly Population: The ARIC Study.
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McNamara et al., Circulation. 2019

Left Atrial Electromechanical Remodeling Following 2 Years of High-Intensity Exercise Training in Sedentary Middle-Aged Adults.
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Baca-Motes et al., Contemp Clin Trials Commun., 2019

Digital recruitment and enrollment in a remote nationwide trial of screening for undiagnosed atrial fibrillation: Lessons from the randomized, controlled mSToPS trial.
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Pang et al., Neurology, 2019

Cardiac electrical instability in newly diagnosed/chronic epilepsy tracked by Holter and ECG patch.
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Schultz et al., Congenit Heart Dis., 2019

Extended cardiac ambulatory rhythm monitoring in adults with congenital heart disease: Arrhythmia detection and impact of extended monitoring.
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Donnellan et al., Circ Arrhythm Electrophysiol., 2019

Outcomes of Atrial Fibrillation Ablation in Morbidly Obese Patients Following Bariatric Surgery Compared With a Nonobese Cohort.
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Gunda et al., J Cardiovasc Electrophysiol. 2019

Consequences of chronic frequent premature atrial contractions: Association with cardiac arrhythmias and cardiac structural changes.
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Wadia et al., Congenit Heart Dis., 2019

Postoperative and short-term atrial tachyarrhythmia burdens after transcatheter vs surgical pulmonary valve replacement among congenital heart disease patients.
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Mullis et al., Heart Rhythm, 2019

Fluctuations in Premature Ventricular Contraction Burden Can Affect Medical Assessment and Management.
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Rogovoy et al., J Am Heart Assoc., 2019

Hemodialysis Procedure-Associated Autonomic Imbalance and Cardiac Arrhythmias: Insights From Continuous 14-Day ECG Monitoring.
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Taylor et al., Neurology., 2019

Cardiac and skeletal muscle effects in the randomized HOPE-Duchenne trial.
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Eysenck et al., Journal of Interventional Cardiac Electrophysiology, 2019

A Randomized Trial Evaluating the Accuracy of AF Detection by Four External Ambulatory ECG Monitors Compared to Permanent Pacemaker AF Detection.
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Hannun et al., Nature Medicine, 2019

Cardiologist-Level Arrhythmia Detection and Classification in Ambulatory Electrocardiograms Using a Deep Neural Network.
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Wineinger et al., Heart Rhythm Journal, 2019

Identification of Paroxysmal Atrial Fibrillation Subtypes in Over 13,000 Individuals.
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Opondo et al., Circ Arrhythm Electrophysiol., 2018

Does High-Intensity Endurance Training Increase the Risk of Atrial Fibrillation.
Zio by iRhythm is dedicated to providing clinicians with peer-reviewed scientific evidence. With over 100 publications, Zio is the industry leader that first identified and met the need for long-term continuous monitoring.
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Heckbert et al., Journal of Electrocardiology, 2018

Yield and Consistency of Arrhythmia Detection With Patch Electrocardiographic Monitoring: The Multi-Ethnic Study of Atherosclerosis.
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Reed et al., Emergency Care Journal, 2018

Brain Natriuretic Peptide and High-Sensitivity Troponin at 3 Hours Post Emergency Department Attendance With Unexplained Syncope Predict 90 Day Outcome.
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Lutsey et al., Nutrients, 2018

A Pilot Randomized Trial of Oral Magnesium Supplementation on Supraventricular Arrhythmias.
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Steinhubl et al., JAMA, 2018

Effect of a Home-Based Wearable Continuous ECG Monitoring Patch on Detection of Undiagnosed Atrial Fibrillation: The mSToPS Randomized Clinical Trial.
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Wadia et al., Heart., 2018

Ventricular arrhythmia burden after transcatheter versus surgical pulmonary valve replacement.
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Reed et al., Emergency Medicine Journal, 2018

Diagnostic Yield of an Ambulatory Patch Monitor in Patients With Unexplained Syncope After Initial Evaluation in the Emergency Department: The PATCH-ED Study.
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Go et al., JAMA Cardiology, 2018

Association of Burden of Atrial Fibrillation With Risk of Ischemic Stroke in Adults With Paroxysmal Atrial Fibrillation: The KP-RHYTHM Study.
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Zhang et al., Pacing Clin Electrophysiol., 2018

Feasibility of using a leadless patch monitor in community cohort studies: The Multi-ethnic Study of Atherosclerosis.
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Muse et al., PLOS Medicine, 2018

Validation of a Genetic Risk Score for Atrial Fibrillation: A Prospective Multicenter Cohort Study.
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  1. Data on file. iRhythm Technologies, 2023.

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